Xenopus morpholino screen

Common name:	Tbx6
X. tropicalis clone name:	TGas124n10
Accession:	CR942588.2

Morpholino-1
MO sequence	GCTCAGTACATTGGGTGCAGGGACC
Phenotype	Embryos develop apparently normally through gastrulation but by tailbud stage they exhibit a short A-P axis due to a tailbud truncation and are slightly ventralised. At tadpole stage embryos have retarded tail development and pericardial oedema.
Phenotypic Class	SHORT AXIS
Synphenotype Group	SHORT AXIS SURVIVING TO TADPOLE

MO-1 phenotypes

control - gastrula	control - tailbud	control - tadpole


morpholino - gastrula	morpholino - tailbud	morpholino - tadpole

Morpholino-2
MO sequence	AGCTCTGAGTGGTACATTCCGGCTC
Phenotype	Embryos develop apparently normally through gastrulation but by tailbud stage they exhibit a short A-P axis due to a tailbud truncation and are slightly ventralised. At tadpole stage embryos have short up-turned tails and mild pericardial oedema.
Phenotypic Class	BENT AXIS
Synphenotype Group	SHORT BODY, UP-TURNED TAIL AND DORSALISED

MO-2 phenotypes

control.2 - gastrula	control.2 - tailbud	control.2 - tadpole


morpholino.2 - gastrula	morpholino.2 - tailbud	morpholino.2 - tadpole

Expression data

expression - gastrula	expression - neurula	expression - tailbud	expression - tadpole

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Expression profile

Expression levels, estimated from EST data, relative to total library clones.

		0.1%																																																																				0.1%
	Stage specific expression levels																																																																				Tissue specific expression levels
	stage			1				5					10					15					20					25					30					35					40					45					50					55					60						tissue			Bod	Brn	Fat	Hrt	Int	Kid	Liv	Lun	Mus	Ova	Ovi	Ski	Spl	Sto	Te