Xenopus morpholino screen

Common name:	REEP4/Ypt Homolog
X. tropicalis clone name:	TEgg068f10
Accession:	CR926301.2

Morpholino-1
MO sequence	CGAGAGATGATCCAGGATACCATTC
Phenotype	Embryos appear to develop normally to tailbud stage. However, by tadpole stage embryos injected with a low dose, although appearing relatively normal, are paralysed. At higher doses, but at the same stage, embryos exhibit defects in somitogenesis.
Phenotypic Class	MOTILITY DEFECTS
Synphenotype Group	MILDLY KINKED TAIL AND MOTILITY DEFECTS

MO-1 phenotypes

control - gastrula	control - tailbud	control - tadpole


morpholino - gastrula	morpholino - tailbud	morpholino - tadpole

Morpholino-2
MO sequence	CCTCACTGACACTGTCTCCCTCACA
Phenotype	Embryos appear to develop normally through early gastrulation however, by tailbud stage embryos are shortened along the A-P axis. At tadpole stage embryos appear short exhibiting defects in somitogenesis.
Phenotypic Class	BENT AXIS
Synphenotype Group	SHORT BODY, UP-TURNED TAIL AND DORSALISED

MO-2 phenotypes

control.2 - gastrula	control.2 - tailbud	control.2 - tadpole


morpholino.2 - gastrula	morpholino.2 - tailbud	morpholino.2 - tadpole

Expression data

expression - gastrula	expression - neurula	expression - tailbud	expression - tadpole

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Expression profile

Expression levels, estimated from EST data, relative to total library clones.

		0.01%																																																																				0.01%
	Stage specific expression levels																																																																				Tissue specific expression levels
	stage			1				5					10					15					20					25					30					35					40					45					50					55					60						tissue			Bod	Brn	Fat	Hrt	Int	Kid	Liv	Lun	Mus	Ova	Ovi	Ski	Spl	Sto	Te